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Welcome to Wellness Wisdom—Your Weekly Guide to Thriving After 50

Each week, you’ll find simple, effective health tips, inspiring insights, and practical strategies designed to help you feel your best—physically, mentally, and emotionally.

No matter where you are on your wellness journey, we’re here to support, encourage, and walk alongside you every step of the way.

Let’s keep growing stronger, healthier, and more energized—together.

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Wellness Wisdom Weekly - Your Guide to Living Well After 50

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November 2025 Issue 31

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The Four Horsemen Part 2 reveals the four main threats that silently shorten most lives: heart disease, cancer, neurodegenerative disease, and metabolic dysfunction. This issue breaks down why these “Four Horsemen” matter—and what we can start doing now to outlive them.

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November Newsletters

Issue 29- Overview of the Book Outlive teaches that longevity isn’t just about living longer—it’s about staying strong, sharp, and independent as we age. This overview introduces Attia’s core ideas on proactive health, the Four Horsemen of disease, and why the choices we make now shape the life we get to live later.

Issue 30 - Setting the Long Game Part 1 of the book challenges us to stop thinking in “one-year health goals” and start planning for the strength, mobility, and independence we want decades from now. This issue explains how to build a long-range strategy for aging well by training today for the abilities we’ll need at 80, 90, and beyond.

Issue 31 - The Four Horsemen Part 2 reveals the four main threats that silently shorten most lives: heart disease, cancer, neurodegenerative disease, and metabolic dysfunction. This issue breaks down why these “Four Horsemen” matter—and what we can start doing now to outlive them.

Issue 32 - Tactics & Tools of Longevity Part 3 moves from theory to action, outlining the daily habits, measurements, and lifestyle levers that have the greatest impact on extending healthspan. This issue focuses on the four big drivers of longevity—exercise, nutrition, sleep, and emotional health—and how to start applying them with purpose and precision.

Welcome to Issue 31 of Wellness Wisdom!

The Four Horsemen: The Science and Art of Longevity by Dr. Peter Attia

  • Introduction

  • Heart Disease: The Silent Architect of Decline

  • Cancer: A Game of Early Detection and Prevention

  • Neurodegenerative Disease: Protecting the Brain Before It's in Trouble

  • Metabolic Dysfunction: The Hidden Root of Modern Illness

  • Strength and Muscle: Your Overlooked Longevity Armor

  • Testing, Tracking, and Taking Control

  • Your Future Self is Counting on You

  • Fit After 50 Blueprint

🧭 Introduction

Welcome back to Wellness Wisdom Weekly! In Issue #31, we continue our deep dive into Outlive: The Science & Art of Longevity by Peter Attia, MD.

Today, we explore Part Two, where Attia introduces what he calls “The Four Horsemen”—the four major chronic conditions that most threaten long, healthy lives. They’re not sudden. They’re not dramatic. They are slow, silent, and relentlessly common.

The Four Horsemen are:

  • Heart disease

  • Cancer

  • Neurodegenerative disease

  • Metabolic dysfunction

Attia argues—and I fully agree—that longevity isn’t about adding more years at the end, but about improving the quality of the years in the middle.

To do that, we must understand these Four Horsemen and take action long before symptoms ever appear.

❤️ Heart Disease: The Silent Architect of Decline

Cardiovascular disease is still the #1 killer in the United States, yet it often progresses with no symptoms until it’s too late.

Attia calls heart disease one of the most “predictable” Horsemen—because the risk builds slowly and quietly for decades before showing itself.

Key drivers include:

  • High LDL cholesterol

  • Chronic inflammation

  • High blood pressure

  • Poor glucose control

  • Lack of strength and aerobic fitness

What you can do now:

  • Get regular blood panels, including ApoB (the gold-standard marker for cardiovascular risk).

  • Build a consistent aerobic base—zone 2 training is your friend.

  • Strength train twice a week to support healthy blood pressure and insulin sensitivity.

  • Reduce refined sugars and ultra-processed foods, which contribute to inflammation.

Small, consistent habits dramatically reduce heart-disease risk.

The goal is not perfection—it’s protection.

🎗️ Cancer: A Game of Early Detection and Prevention

Cancer is the Horseman that most people fear—but often misunderstand. Attia emphasizes that cancer is fundamentally a disease of aging. The longer we live, the more time our cells have to accumulate genetic damage.

But early detection dramatically improves outcomes.

Two truths Attia highlights:

  • Cancer often grows for years before it is detectable.

  • Many cancers can be treated or slowed if found early.

Steps you can take now:

  • Stay up-to-date with screenings: colonoscopy, mammogram, PSA, skin checks.

  • Consider advanced screenings like full-body MRI or emerging blood-based early detection tests.

  • Reduce chronic inflammation through nutrition and movement.

  • Avoid tobacco, excessive alcohol, and long-term sun exposure.

Cancer thrives in the shadows. Awareness and action keep it from sneaking up on us.

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🧠 Neurodegenerative Disease: Protecting the Brain Before It’s in Trouble

Neurodegenerative diseases—Alzheimer’s, Parkinson’s, and other forms of dementia—are among the most devastating Horsemen because they chip away at identity, memory, and independence.

And here’s the wake-up call:

Brain decline begins 20–30 years before symptoms appear.

Attia’s philosophy: Prevention begins now.

What supports brain health:

  • Quality sleep

  • Regular movement

  • Continuous learning

  • Social connection

  • Managing metabolic health (insulin resistance harms the brain)

You can stimulate neuroplasticity at any age by doing challenging things: learning a new skill, picking up an instrument, reading difficult books, practicing balance, or even social engagement.

Fighting this Horseman is less about medicine and more about lifestyle.

🍽️ Metabolic Dysfunction: The Hidden Root of Modern Illness

Metabolic dysfunction is the Horseman most people overlook—but it influences all the others. Attia argues that metabolic disease—insulin resistance, type 2 diabetes, fatty liver, and obesity—is the most preventable threat to long-term health.

And it often starts earlier than we think.

The early signs include:

  • Increasing belly fat

  • Fatigue

  • High fasting glucose

  • Elevated triglycerides

  • Brain fog

  • A1C creeping upward

Attia calls metabolic health the foundation of longevity.

Practical steps:

  • Cut back on sugar, refined carbohydrates, and processed snacks.

  • Prioritize protein.

  • Embrace resistance training, which improves insulin sensitivity.

  • Consider time-restricted eating or consistent fasting windows.

  • Test often—what gets measured gets managed.

If you win the battle against metabolic dysfunction, you influence every other Horseman.

💪 Strength and Muscle: Your Overlooked Longevity Armor

While Attia focuses on disease prevention, he repeatedly emphasizes that muscle is medicine—especially after age 50.

Why muscle matters:

  • It helps regulate blood sugar.

  • It protects bones and joints.

  • It supports balance and prevents falls.

  • It produces hormones essential for aging well.

  • It provides the functional strength needed for independence.

Attia urges readers to think about the physical requirements of life at age 80 or 90—and begin training for that reality today.

Two priorities:

  • Zone 2 aerobic work (for heart health and metabolic health)

  • Strength training (for longevity, mobility, and resilience)

You’re not just working out—you’re building your future.

🩺 Testing, Tracking, and Taking Control

One of Attia’s biggest messages is this: don’t wait for disease to show up.

Be proactive. Not reactive.

Longevity is powered by information—and today, we have more access to data than any generation before us.

Recommended baseline labs and screenings:

  • ApoB and lipid panel

  • Fasting glucose, fasting insulin, and A1C

  • High-sensitivity CRP (inflammation)

  • Liver enzymes

  • Kidney function

  • Vitamin D

  • DEXA scan for muscle and fat distribution

  • Coronary calcium scan around age 45–55

Tracking isn’t about fear—it’s about empowerment.

Knowing your numbers gives you the opportunity to steer your health instead of guessing.

🌅 Your Future Self Is Counting on You

Attia’s message in Outlive is simple but profound:

We don’t age and then suddenly fall apart. We fall apart because we don’t prepare to age.

The Four Horsemen are not inevitable.

  • They’re addressable.

  • They’re influenceable.

  • They’re slow-moving—but only if we start moving too.

Your future self—20, 30, 40 years from now—is relying on the choices you make today:

  • Move your body.

  • Eat with intention.

  • Track your health.

  • Build strength.

  • Reduce sugar.

  • Sleep deeply.

  • Honor your stress levels.

  • And above all—stay curious about your health.

At West Egg Living, we believe in aging with purpose, energy, and joy.

You deserve a long healthspan, not just a long lifespan.

Let’s outlive the Four Horsemen together.

Until next week—stay strong, stay curious, and stay well.

Fit After 50 Blueprint

💪 Ready to take control of your health after 50?

Our Fit After 50 Blueprint is your step-by-step guide to building strength, boosting energy, and regaining confidence—no matter where you’re starting from.

Designed specifically for men and women over 50, it focuses on simple, sustainable habits that work with your body, not against it.

Start today and build the healthy, active future you deserve!

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📣 Stay Connected: Don't forget to visit West Egg Living on Facebook!!!

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If you’ve missed a past issue of the West Egg Wellness Wisdom Newsletter, no worries—we’ve got you covered! Our full archive is now available, making it easy to revisit every article, tip, and story we’ve shared.

Whether you’re looking to catch up or just browse for inspiration, you’ll find it all in one place. Dive in and explore at your own pace!

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If you’re new to West Egg Wellness 50+, be sure to click on the Getting Started icon. There, you’ll find free downloadable materials designed to help you take those first steps toward better health and nutrition. From simple meal planning guides to beginner-friendly fitness tips, these resources are created with you in mind. It’s a great way to jumpstart your wellness journey—don’t miss it!

If you have any questions, thoughts, or comments you'd like to share, I'm always happy to hear from you - just send a message to info@westeggliving.com

I'm here to help!

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Thank you for joining us for this edition of Wellness Wisdom! We hope you found inspiration, encouragement, and a few practical takeaways to support your wellness journey. Remember, lasting health isn’t about perfection — it’s about small, consistent steps.

We’re honored to walk alongside you as you create a stronger, more vibrant life after 50. Stay tuned for next week’s issue packed with more tips, insights, and motivation. Until then, be kind to yourself and keep moving forward — you’ve got this!

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5 Comments
Tim

I love the video on this one.

Marlene

I will try dinking water every hourr like I am trying to go 250 steps each hour.. Encouraging idea.

Pam

This is great information. I love the new layout. I cannot wait for the next edition!!!

Tim

Thanks Riaan.

Riaan

Great article!

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